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Therapeutic potential of the metabolic modulator phenformin in targeting the stem cell compartment in melanoma
Melanoma is the most dangerous and treatment-resistant skin cancer. Tumor resistance and recurrence are due to the persistence in the patient of aggressive cells with stem cell features, the cancer stem cells (CSC). Recent evidences have shown that CSC display a distinct metabolic profile as compare...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351679/ https://www.ncbi.nlm.nih.gov/pubmed/28036292 http://dx.doi.org/10.18632/oncotarget.14321 |