c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas

High-grade gliomas (HGG) are the most common brain tumors, with an average survival time of 14 months. A glioma-CpG island methylator phenotype (G-CIMP), associated with better clinical outcome, has been described in low and high-grade gliomas. Mutation of IDH1 is known to drive the G-CIMP status. I...

Descripción completa

Detalles Bibliográficos
Autores principales: Heiland, Dieter H, Ferrarese, Roberto, Claus, Rainer, Dai, Fangping, Masilamani, Anie P, Kling, Eva, Weyerbrock, Astrid, Kling, Teresia, Nelander, Sven, Carro, Maria S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351681/
https://www.ncbi.nlm.nih.gov/pubmed/28036297
http://dx.doi.org/10.18632/oncotarget.14330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351681/
https://www.ncbi.nlm.nih.gov/pubmed/28036297
http://dx.doi.org/10.18632/oncotarget.14330

Ejemplares similares