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c-Jun-N-terminal phosphorylation regulates DNMT1 expression and genome wide methylation in gliomas
High-grade gliomas (HGG) are the most common brain tumors, with an average survival time of 14 months. A glioma-CpG island methylator phenotype (G-CIMP), associated with better clinical outcome, has been described in low and high-grade gliomas. Mutation of IDH1 is known to drive the G-CIMP status. I...
Autores principales: | Heiland, Dieter H, Ferrarese, Roberto, Claus, Rainer, Dai, Fangping, Masilamani, Anie P, Kling, Eva, Weyerbrock, Astrid, Kling, Teresia, Nelander, Sven, Carro, Maria S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351681/ https://www.ncbi.nlm.nih.gov/pubmed/28036297 http://dx.doi.org/10.18632/oncotarget.14330 |
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