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The IgH 3’ regulatory region and c-myc-induced B-cell lymphomagenesis

Deregulation and mutations of c-myc have been reported in multiple mature B-cell malignancies such as Burkitt lymphoma, myeloma and plasma cell lymphoma. After translocation into the immunoglobulin heavy chain (IgH) locus, c-myc is constitutively expressed under the control of active IgH cis-regulat...

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Detalles Bibliográficos
Autores principales: Ghazzaui, Nour, Saintamand, Alexis, Issaoui, Hussein, Vincent-Fabert, Christelle, Denizot, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351691/
https://www.ncbi.nlm.nih.gov/pubmed/27729620
http://dx.doi.org/10.18632/oncotarget.12535