Recent development of ATP-competitive small molecule phosphatidylinostitol-3-kinase inhibitors as anticancer agents

Phosphatidylinostitol-3-kinase (PI3K) is the potential anticancer target in the PI3K/Akt/ mTOR pathway. Here we reviewed the ATP-competitive small molecule PI3K inhibitors in the past few years, including the pan Class I PI3K inhibitors, the isoform-specific PI3K inhibitors and/or the PI3K/mTOR dual...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Wan, Wen-zhu, Li, Yan, Zhou, Guan-lian, Liu, Xin-guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351699/
https://www.ncbi.nlm.nih.gov/pubmed/27769061
http://dx.doi.org/10.18632/oncotarget.12742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351699/
https://www.ncbi.nlm.nih.gov/pubmed/27769061
http://dx.doi.org/10.18632/oncotarget.12742

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