LC–MS/MS assay for quantitation of enalapril and enalaprilat in plasma for bioequivalence study in Indian subjects

BACKGROUND: Enalapril (EPL) is an angiotensin-converting enzyme inhibitor for the treatment of hypertension and chronic heart failure. Enalaprilat (EPLT) is an active metabolite that contributes to the overall activity of EPL. AIM: To quantitate EPL along with its metabolite EPLT using LC–MS/MS, a b...

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Detalles Bibliográficos
Autores principales: Halder, Dhiman, Dan, Shubhasis, Pal, Murari Mohun, Biswas, Easha, Chatterjee, Nilendra, Sarkar, Pradipta, Halder, Umesh Chandra, Pal, Tapan Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351712/
https://www.ncbi.nlm.nih.gov/pubmed/28344828
http://dx.doi.org/10.4155/fsoa-2016-0071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351712/
https://www.ncbi.nlm.nih.gov/pubmed/28344828
http://dx.doi.org/10.4155/fsoa-2016-0071

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