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Perinatal high methyl donor alters gene expression in IGF system in male offspring without altering DNA methylation

AIM: To investigate the effect of a protein restriction and a supplementation with methyl donor nutrients during fetal and early postnatal life on the expression and epigenetic state of imprinted genes from the IGF system. MATERIALS & METHODS: Pregnant female rats were fed a protein-restricted d...

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Detalles Bibliográficos
Autores principales: Amarger, Valérie, Giudicelli, Fanny, Pagniez, Anthony, Parnet, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351714/
https://www.ncbi.nlm.nih.gov/pubmed/28344827
http://dx.doi.org/10.4155/fsoa-2016-0077