Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy

AIMS: Dilated cardiomyopathy (DCM) is an important cause of heart failure with a strong familial component. We performed an exome-wide array-based association study (EWAS) to assess the contribution of missense variants to sporadic DCM. METHODS AND RESULTS: 116,855 single nucleotide variants (SNVs)...

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Detalles Bibliográficos
Autores principales: Esslinger, Ulrike, Garnier, Sophie, Korniat, Agathe, Proust, Carole, Kararigas, Georgios, Müller-Nurasyid, Martina, Empana, Jean-Philippe, Morley, Michael P., Perret, Claire, Stark, Klaus, Bick, Alexander G., Prasad, Sanjay K., Kriebel, Jennifer, Li, Jin, Tiret, Laurence, Strauch, Konstantin, O'Regan, Declan P., Marguiles, Kenneth B., Seidman, Jonathan G., Boutouyrie, Pierre, Lacolley, Patrick, Jouven, Xavier, Hengstenberg, Christian, Komajda, Michel, Hakonarson, Hakon, Isnard, Richard, Arbustini, Eloisa, Grallert, Harald, Cook, Stuart A., Seidman, Christine E., Regitz-Zagrosek, Vera, Cappola, Thomas P., Charron, Philippe, Cambien, François, Villard, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351854/
https://www.ncbi.nlm.nih.gov/pubmed/28296976
http://dx.doi.org/10.1371/journal.pone.0172995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351854/
https://www.ncbi.nlm.nih.gov/pubmed/28296976
http://dx.doi.org/10.1371/journal.pone.0172995

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