Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain

Dense genotyping approaches have revealed much about the genetic architecture both of gene expression and disease susceptibility. However, assigning causality to genetic variants associated with a transcriptomic or phenotypic trait presents a far greater challenge. The development of epigenomic reso...

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Detalles Bibliográficos
Autores principales: Handel, Adam E., Gallone, Giuseppe, Zameel Cader, M., Ponting, Chris P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351933/
https://www.ncbi.nlm.nih.gov/pubmed/27798116
http://dx.doi.org/10.1093/hmg/ddw369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351933/
https://www.ncbi.nlm.nih.gov/pubmed/27798116
http://dx.doi.org/10.1093/hmg/ddw369

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