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Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain
Dense genotyping approaches have revealed much about the genetic architecture both of gene expression and disease susceptibility. However, assigning causality to genetic variants associated with a transcriptomic or phenotypic trait presents a far greater challenge. The development of epigenomic reso...
Autores principales: | Handel, Adam E., Gallone, Giuseppe, Zameel Cader, M., Ponting, Chris P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351933/ https://www.ncbi.nlm.nih.gov/pubmed/27798116 http://dx.doi.org/10.1093/hmg/ddw369 |
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