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The dual orexin receptor antagonist TCS1102 does not affect reinstatement of nicotine-seeking

The orexin/hypocretin system is important for appetitive motivation towards multiple drugs of abuse, including nicotine. Both OX(1) and OX(2) receptors individually have been shown to influence nicotine self-administration and reinstatement. Due to the increasing clinical use of dual orexin receptor...

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Detalles Bibliográficos
Autores principales: Khoo, Shaun Yon-Seng, McNally, Gavan P., Clemens, Kelly J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351999/
https://www.ncbi.nlm.nih.gov/pubmed/28296947
http://dx.doi.org/10.1371/journal.pone.0173967