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The dual orexin receptor antagonist TCS1102 does not affect reinstatement of nicotine-seeking
The orexin/hypocretin system is important for appetitive motivation towards multiple drugs of abuse, including nicotine. Both OX(1) and OX(2) receptors individually have been shown to influence nicotine self-administration and reinstatement. Due to the increasing clinical use of dual orexin receptor...
Autores principales: | Khoo, Shaun Yon-Seng, McNally, Gavan P., Clemens, Kelly J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351999/ https://www.ncbi.nlm.nih.gov/pubmed/28296947 http://dx.doi.org/10.1371/journal.pone.0173967 |
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