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Glioprotection of Retinal Astrocytes After Intravitreal Administration of Memantine in the Mouse Optic Nerve Crush Model

BACKGROUND: In glaucoma, non-intraocular pressure (IOP)-related risk factors can result in increased levels of extracellular glutamate, which triggers a cascade of neurodegeneration characterized by the excessive activation of N-methyl-D-aspartate (NMDA). The purpose of our study was to evaluate the...

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Detalles Bibliográficos
Autores principales: Maciulaitiene, Ruta, Pakuliene, Giedre, Kaja, Simon, Pauza, Dainius Haroldas, Kalesnykas, Giedrius, Januleviciene, Ingrida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352005/
https://www.ncbi.nlm.nih.gov/pubmed/28265105
http://dx.doi.org/10.12659/MSM.899699