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Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas

Aerobic glycolysis is one of the emerging hallmarks of cancer cells. In this study, we investigated the relationship between blocking mitochondrial pyruvate carrier (MPC) with MPC blocker UK5099 and the metabolic alteration as well as aggressive features of esophageal squamous carcinoma. It was foun...

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Detalles Bibliográficos
Autores principales: Li, Yaqing, Li, Xiaoran, Kan, Quancheng, Zhang, Mingzhi, Li, Xiaoli, Xu, Ruiping, Wang, Junsheng, Yu, Dandan, Goscinski, Mariusz Adam, Wen, Jian-Guo, Nesland, Jahn M., Suo, Zhenhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352034/
https://www.ncbi.nlm.nih.gov/pubmed/27911865
http://dx.doi.org/10.18632/oncotarget.13717