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Zoledronic acid impairs stromal reactivity by inhibiting M2-macrophages polarization and prostate cancer-associated fibroblasts
Zoledronic acid (ZA) is a biphosphonate used for osteoporosis treatment and also proved to be effective to reduce the pain induced by bone metastases when used as adjuvant therapy in solid cancers. However, it has been recently proposed that ZA could have direct anti-tumour effects, although the mol...
Autores principales: | Comito, Giuseppina, Segura, Coral Pons, Taddei, Maria Letizia, Lanciotti, Michele, Serni, Sergio, Morandi, Andrea, Chiarugi, Paola, Giannoni, Elisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352046/ https://www.ncbi.nlm.nih.gov/pubmed/27223431 http://dx.doi.org/10.18632/oncotarget.9497 |
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