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Cancer-associated fibroblasts promote cancer cell growth through a miR-7-RASSF2-PAR-4 axis in the tumor microenvironment

Cancer-associated fibroblasts (CAFs), a major component of cancer stroma, play an important role in cancer progression but little is known about how CAFs affect tumorigenesis and development. MicroRNAs (miRNAs) are small non-coding RNAs that can negatively regulate target mRNA expression at post-tra...

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Detalles Bibliográficos
Autores principales: Shen, Zongze, Qin, Xing, Yan, Ming, Li, Rongrong, Chen, Gang, Zhang, Jianjun, Chen, Wantao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352055/
https://www.ncbi.nlm.nih.gov/pubmed/27901488
http://dx.doi.org/10.18632/oncotarget.13609