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Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts

Acto-myosin contractility in carcinoma-associated fibroblasts leads to assembly of the tumor extracellular matrix. The pro-inflammatory cytokine LIF governs fibroblast activation in cancer by regulating the myosin light chain 2 activity. So far, however, how LIF mediates cytoskeleton contractility r...

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Detalles Bibliográficos
Autores principales: Bonan, Stephanie, Albrengues, Jean, Grasset, Eloise, Kuzet, Sanya-Eduarda, Nottet, Nicolas, Bourget, Isabelle, Bertero, Thomas, Mari, Bernard, Meneguzzi, Guerrino, Gaggioli, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352056/
https://www.ncbi.nlm.nih.gov/pubmed/27901489
http://dx.doi.org/10.18632/oncotarget.13610