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Targeting tissue factor as a novel therapeutic oncotarget for eradication of cancer stem cells isolated from tumor cell lines, tumor xenografts and patients of breast, lung and ovarian cancer

Targeting cancer stem cell (CSC) represents a promising therapeutic approach as it can potentially fight cancer at its root. The challenge is to identify a surface therapeutic oncotarget on CSC. Tissue factor (TF) is known as a common yet specific surface target for cancer cells and tumor neovascula...

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Detalles Bibliográficos
Autores principales: Hu, Zhiwei, Xu, Jie, Cheng, Jijun, McMichael, Elizabeth, Yu, Lianbo, Carson, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352071/
https://www.ncbi.nlm.nih.gov/pubmed/27903969
http://dx.doi.org/10.18632/oncotarget.13644