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NEDD9 may regulate hepatocellular carcinoma cell metastasis by promoting epithelial-mesenchymal-transition and stemness via repressing Smad7

Overexpression of neural precursor cell expressed, developmentally downregulated 9 (NEDD9) is a prognostic marker of many cancers, including hepatocellular carcinoma (HCC). However, the functions and mechanisms of NEDD9 are unclear. We found that upregulation of NEDD9 promoted migration, invasion an...

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Detalles Bibliográficos
Autores principales: Wang, Zhipeng, Shen, Min, Lu, Peng, Li, Xiao, Zhu, Shaojun, Yue, Shuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352091/
https://www.ncbi.nlm.nih.gov/pubmed/27974675
http://dx.doi.org/10.18632/oncotarget.13852