Tumorigenicity of Ewing sarcoma is critically dependent on the trithorax proteins MLL1 and menin

Developmental transcription programs are epigenetically regulated by the competing actions of polycomb and trithorax (TrxG) protein complexes, which repress and activate genes, respectively. Ewing sarcoma is a developmental tumor that is associated with widespread de-regulation of developmental tran...

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Detalles Bibliográficos
Autores principales: Svoboda, Laurie K., Bailey, Natashay, Van Noord, Raelene A., Krook, Melanie A., Harris, Ashley, Cramer, Cassondra, Jasman, Brooke, Patel, Rajiv M., Thomas, Dafydd, Borkin, Dmitry, Cierpicki, Tomasz, Grembecka, Jolanta, Lawlor, Elizabeth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352134/
https://www.ncbi.nlm.nih.gov/pubmed/27888797
http://dx.doi.org/10.18632/oncotarget.13444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352134/
https://www.ncbi.nlm.nih.gov/pubmed/27888797
http://dx.doi.org/10.18632/oncotarget.13444

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