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miR-103 inhibits proliferation and sensitizes hemopoietic tumor cells for glucocorticoid-induced apoptosis

Glucocorticoid (GC) hormones are an important ingredient of leukemia therapy since they are potent inducers of lymphoid cell apoptosis. However, the development of GC resistance remains an obstacle in GC-based treatment. In the present investigation we found that miR-103 is upregulated in GC-sensiti...

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Detalles Bibliográficos
Autores principales: Kfir-Erenfeld, Shlomit, Haggiag, Noa, Biton, Moshe, Stepensky, Polina, Assayag-Asherie, Nathalie, Yefenof, Eitan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352135/
https://www.ncbi.nlm.nih.gov/pubmed/27888798
http://dx.doi.org/10.18632/oncotarget.13447