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TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF

Mutations in the gene encoding transcription factor TFAP2A result in pigmentation anomalies in model organisms and premature hair graying in humans. However, the pleiotropic functions of TFAP2A and its redundantly-acting paralogs have made the precise contribution of TFAP2-type activity to melanocyt...

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Detalles Bibliográficos
Autores principales: Seberg, Hannah E., Van Otterloo, Eric, Loftus, Stacie K., Liu, Huan, Bonde, Greg, Sompallae, Ramakrishna, Gildea, Derek E., Santana, Juan F., Manak, J. Robert, Pavan, William J., Williams, Trevor, Cornell, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352137/
https://www.ncbi.nlm.nih.gov/pubmed/28249010
http://dx.doi.org/10.1371/journal.pgen.1006636