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TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF
Mutations in the gene encoding transcription factor TFAP2A result in pigmentation anomalies in model organisms and premature hair graying in humans. However, the pleiotropic functions of TFAP2A and its redundantly-acting paralogs have made the precise contribution of TFAP2-type activity to melanocyt...
Autores principales: | Seberg, Hannah E., Van Otterloo, Eric, Loftus, Stacie K., Liu, Huan, Bonde, Greg, Sompallae, Ramakrishna, Gildea, Derek E., Santana, Juan F., Manak, J. Robert, Pavan, William J., Williams, Trevor, Cornell, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352137/ https://www.ncbi.nlm.nih.gov/pubmed/28249010 http://dx.doi.org/10.1371/journal.pgen.1006636 |
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