Dioscin augments HSV-tk-mediated suicide gene therapy for melanoma by promoting connexin-based intercellular communication

Suicide gene therapy is a promising strategy against melanoma. However, the low efficiency of the gene transfer technique can limit its application. Our preliminary data showed that dioscin, a glucoside saponin, could upregulate the expression of connexins Cx26 and Cx43, major components of gap junc...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Jianyong, Zhang, Guangxian, Li, Bin, Wu, Yingya, Liu, Xijuan, Tan, Yuhui, Du, Biaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352197/
https://www.ncbi.nlm.nih.gov/pubmed/27903977
http://dx.doi.org/10.18632/oncotarget.13655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352197/
https://www.ncbi.nlm.nih.gov/pubmed/27903977
http://dx.doi.org/10.18632/oncotarget.13655

Ejemplares similares