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Dioscin augments HSV-tk-mediated suicide gene therapy for melanoma by promoting connexin-based intercellular communication

Suicide gene therapy is a promising strategy against melanoma. However, the low efficiency of the gene transfer technique can limit its application. Our preliminary data showed that dioscin, a glucoside saponin, could upregulate the expression of connexins Cx26 and Cx43, major components of gap junc...

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Detalles Bibliográficos
Autores principales:	Xiao, Jianyong, Zhang, Guangxian, Li, Bin, Wu, Yingya, Liu, Xijuan, Tan, Yuhui, Du, Biaoyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352197/ https://www.ncbi.nlm.nih.gov/pubmed/27903977 http://dx.doi.org/10.18632/oncotarget.13655

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