Critical role of SP thymocyte motility in regulation of thymic output in neonatal Aire(−/−) mice

Autoimmune regulator (Aire) is essential in the perinatal period to prevent the multiorgan autoimmunity. Here we show that Aire-regulated single positive thymocyte trafficking in neonatal period is critical for thymic egress. Reduced thymic emigration was found in Aire(−/−) mice during neonatal peri...

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Detalles Bibliográficos
Autores principales: Jin, Rong, Aili, Abudureyimujiang, Wang, Yuqing, Wu, Jia, Sun, Xiuyuan, Zhang, Yu, Ge, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352200/
https://www.ncbi.nlm.nih.gov/pubmed/27965471
http://dx.doi.org/10.18632/oncotarget.13909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352200/
https://www.ncbi.nlm.nih.gov/pubmed/27965471
http://dx.doi.org/10.18632/oncotarget.13909

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