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Critical role of SP thymocyte motility in regulation of thymic output in neonatal Aire(−/−) mice
Autoimmune regulator (Aire) is essential in the perinatal period to prevent the multiorgan autoimmunity. Here we show that Aire-regulated single positive thymocyte trafficking in neonatal period is critical for thymic egress. Reduced thymic emigration was found in Aire(−/−) mice during neonatal peri...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352200/ https://www.ncbi.nlm.nih.gov/pubmed/27965471 http://dx.doi.org/10.18632/oncotarget.13909 |