Epigenetically upregulated WIPF1 plays a major role in BRAF V600E-promoted papillary thyroid cancer aggressiveness

How the BRAF V600E mutation promotes the pathogenesis and aggressiveness of papillary thyroid cancer (PTC) is not completely understood. Here we explored a novel mechanism involving WASP interacting protein family member 1 (WIPF1). In PTC tumors, compared with the wild-type BRAF, BRAF V600E was asso...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Shen, Xiaopei, Liu, Rengyun, Zhu, Guangwu, Bishop, Justin, Xing, Mingzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352205/
https://www.ncbi.nlm.nih.gov/pubmed/27863429
http://dx.doi.org/10.18632/oncotarget.13400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352205/
https://www.ncbi.nlm.nih.gov/pubmed/27863429
http://dx.doi.org/10.18632/oncotarget.13400

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