Gremlin promotes retinal pigmentation epithelial (RPE) cell proliferation, migration and VEGF production via activating VEGFR2-Akt-mTORC2 signaling

Retinopathy of prematurity (ROP) is characterized by late-phase pathologic retinal vasoproliferation. Gremlin is a novel vascular endothelial growth factors (VEGF) receptor 2 (VEGFR2) agonist and promotes angiogenic response. We demonstrated that gremlin expression was significantly increased in ret...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Chen, Zhijun, Cheng, Haixia, Chen, Juan, Qian, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352211/
https://www.ncbi.nlm.nih.gov/pubmed/27894090
http://dx.doi.org/10.18632/oncotarget.13518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352211/
https://www.ncbi.nlm.nih.gov/pubmed/27894090
http://dx.doi.org/10.18632/oncotarget.13518

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