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Discovering sparse transcription factor codes for cell states and state transitions during development

Computational analysis of gene expression to determine both the sequence of lineage choices made by multipotent cells and to identify the genes influencing these decisions is challenging. Here we discover a pattern in the expression levels of a sparse subset of genes among cell types in B- and T-cel...

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Detalles Bibliográficos
Autores principales: Furchtgott, Leon A, Melton, Samuel, Menon, Vilas, Ramanathan, Sharad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352226/
https://www.ncbi.nlm.nih.gov/pubmed/28296636
http://dx.doi.org/10.7554/eLife.20488