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Wide spetcrum mutational analysis of metastatic renal cell cancer: a retrospective next generation sequencing approach

Renal cell cancer (RCC) is characterized by histological and molecular heterogeneity that may account for variable response to targeted therapies. We evaluated retrospectively with a next generation sequencing (NGS) approach using a pre-designed cancer panel the mutation burden of 32 lesions from 22...

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Detalles Bibliográficos
Autores principales: Fiorentino, Michelangelo, Gruppioni, Elisa, Massari, Francesco, Giunchi, Francesca, Altimari, Annalisa, Ciccarese, Chiara, Bimbatti, Davide, Scarpa, Aldo, Iacovelli, Roberto, Porta, Camillo, Virinder, Sarhadi, Tortora, Giampaolo, Artibani, Walter, Schiavina, Riccardo, Ardizzoni, Andrea, Brunelli, Matteo, Knuutila, Sakari, Martignoni, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352324/
https://www.ncbi.nlm.nih.gov/pubmed/27741505
http://dx.doi.org/10.18632/oncotarget.12551