Cargando…

Wide spetcrum mutational analysis of metastatic renal cell cancer: a retrospective next generation sequencing approach

Renal cell cancer (RCC) is characterized by histological and molecular heterogeneity that may account for variable response to targeted therapies. We evaluated retrospectively with a next generation sequencing (NGS) approach using a pre-designed cancer panel the mutation burden of 32 lesions from 22...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fiorentino, Michelangelo, Gruppioni, Elisa, Massari, Francesco, Giunchi, Francesca, Altimari, Annalisa, Ciccarese, Chiara, Bimbatti, Davide, Scarpa, Aldo, Iacovelli, Roberto, Porta, Camillo, Virinder, Sarhadi, Tortora, Giampaolo, Artibani, Walter, Schiavina, Riccardo, Ardizzoni, Andrea, Brunelli, Matteo, Knuutila, Sakari, Martignoni, Guido
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper: Pathology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352324/ https://www.ncbi.nlm.nih.gov/pubmed/27741505 http://dx.doi.org/10.18632/oncotarget.12551

Ejemplares similares

Similarities and Differences between Clear Cell Tubulo-Papillary and Conventional Clear Cell Renal Cell Carcinoma: A Comparative Phenotypical and Mutational Analysis
por: Giunchi, Francesca, et al.
Publicado: (2020)

Dual TMPRSS2:ERG Fusion in a Patient with Lung and Prostate Cancers
por: Giunchi, Francesca, et al.
Publicado: (2020)

Immune Checkpoint Inhibitors and Prostate Cancer: A New Frontier?
por: Modena, Alessandra, et al.
Publicado: (2016)

Renal Tumors with Oncocytic and Papillary Features: A Phenotypic and Genotypic Study
por: Franceschini, Tania, et al.
Publicado: (2021)

Prognostic Value of Beta-Tubulin-3 and c-Myc in Muscle Invasive Urothelial Carcinoma of the Bladder
por: Massari, Francesco, et al.
Publicado: (2015)

Presence of cancer-associated mutations in exhaled breath condensates of healthy individuals by next generation sequencing
por: Youssef, Omar, et al.
Publicado: (2017)

Aberrant expression of ALK and EZH2 in Merkel cell carcinoma
por: Veija, Tuukka, et al.
Publicado: (2017)

Acquired hemophagocytic syndrome: comment to the case report
por: Ciccarese, Chiara, et al.
Publicado: (2015)

Acquired hemophagocytic syndrome in a patient with synovial sarcoma: a case report
por: Ciccarese, Chiara, et al.
Publicado: (2015)

Gut microbiota of patients with different subtypes of gastric cancer and gastrointestinal stromal tumors
por: Sarhadi, Virinder, et al.
Publicado: (2021)

Microbiota Alterations and Their Association with Oncogenomic Changes in Pancreatic Cancer Patients
por: Sammallahti, Heidelinde, et al.
Publicado: (2021)

Oncogenomic Changes in Pancreatic Cancer and Their Detection in Stool
por: Sammallahti, Heidelinde, et al.
Publicado: (2022)

Multiparametric magnetic resonance imaging for the differential diagnosis between granulomatous prostatitis and prostate cancer: a literature review to an intriguing diagnostic challenge
por: Gaudiano, Caterina, et al.
Publicado: (2023)

Gene mutations in stool from gastric and colorectal neoplasia patients by next-generation sequencing
por: Youssef, Omar, et al.
Publicado: (2017)

ADK-VR2, a cell line derived from a treatment-naïve patient with SDC4-ROS1 fusion-positive primarily crizotinib-resistant NSCLC: a novel preclinical model for new drug development of ROS1-rearranged NSCLC
por: Ruzzi, Francesca, et al.
Publicado: (2022)

Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients
por: Ruosaari, Salla, et al.
Publicado: (2008)

Multi-Gene Next-Generation Sequencing Panel for Analysis of BRCA1/BRCA2 and Homologous Recombination Repair Genes Alterations Metastatic Castration-Resistant Prostate Cancer
por: Maloberti, Thais, et al.
Publicado: (2023)

Spa-RQ: an Image Analysis Tool to Visualise and Quantify Spatial Phenotypes Applied to Non-Small Cell Lung Cancer
por: Bao, Jie, et al.
Publicado: (2019)

Current Strategies and Novel Therapeutic Approaches for Metastatic Urothelial Carcinoma
por: Mollica, Veronica, et al.
Publicado: (2020)

True 3q Chromosomal Amplification in Squamous Cell Lung Carcinoma by FISH and aCGH Molecular Analysis: Impact on Targeted Drugs
por: Brunelli, Matteo, et al.
Publicado: (2012)

Transverse prostate maximum sectional area can predict clinically significant prostate cancer in PI-RADS 3 lesions at multiparametric magnetic resonance imaging
por: Gaudiano, Caterina, et al.
Publicado: (2023)

Simultaneous Underexpression of let-7a-5p and let-7f-5p microRNAs in Plasma and Stool Samples from Early Stage Colorectal Carcinoma
por: Ghanbari, Reza, et al.
Publicado: (2016)

DNA methylation changes and somatic mutations as tumorigenic events in Lynch syndrome-associated adenomas retaining mismatch repair protein expression
por: Mäki-Nevala, Satu, et al.
Publicado: (2018)

Targeted Resequencing Reveals ALK Fusions in Non-Small Cell Lung Carcinomas Detected by FISH, Immunohistochemistry, and Real-Time RT-PCR: A Comparison of Four Methods
por: Tuononen, Katja, et al.
Publicado: (2013)

Stool Microbiota Composition Differs in Patients with Stomach, Colon, and Rectal Neoplasms
por: Youssef, Omar, et al.
Publicado: (2018)

Emerging Molecular Technologies in Genitourinary Tumors
por: Giunchi, Francesca, et al.
Publicado: (2018)

A narrative review of individualized treatments of genitourinary tumors: is the future brighter with molecular evaluations?
por: Giunchi, Francesca, et al.
Publicado: (2021)

Molecular Biomarkers in Cancer
por: Sarhadi, Virinder Kaur, et al.
Publicado: (2022)

Angiogenic and signalling proteins correlate with sensitivity to sequential treatment in renal cell cancer
por: Rosa, R, et al.
Publicado: (2013)

Revising PTEN in the Era of Immunotherapy: New Perspectives for an Old Story
por: Piro, Geny, et al.
Publicado: (2019)

454 next generation-sequencing outperforms allele-specific PCR, Sanger sequencing, and pyrosequencing for routine KRAS mutation analysis of formalin-fixed, paraffin-embedded samples
por: Altimari, Annalisa, et al.
Publicado: (2013)

BRAF V600E Status and Stimulated Thyroglobulin at Ablation Time Increase Prognostic Value of American Thyroid Association Classification Systems for Persistent Disease in Differentiated Thyroid Carcinoma
por: Repaci, Andrea, et al.
Publicado: (2019)

Reliability of programmed death ligand 1 (PD-L1) tumor proportion score (TPS) on cytological smears in advanced non-small cell lung cancer: a prospective validation study
por: Ricci, Costantino, et al.
Publicado: (2020)

Prostate chronic inflammation type IV and prostate cancer risk in patients undergoing first biopsy set: Results of a large cohort study
por: Porcaro, Antonio Benito, et al.
Publicado: (2015)

Mesenchymal Stem Cells and Extracellular Vesicles in Osteosarcoma Pathogenesis and Therapy
por: Sarhadi, Virinder Kaur, et al.
Publicado: (2021)

Adjuvant chemotherapy for resected non-small-cell lung cancer: future perspectives for clinical research
por: Bonomi, Maria, et al.
Publicado: (2011)

Is There a Role for Immunotherapy in Prostate Cancer?
por: Rizzo, Alessandro, et al.
Publicado: (2020)

Biomarker analysis in human neoplasias: superior next-generation sequencing on frozen bone marrow cells and on formalin-fixed, paraffin-embedded tumor tissues
por: Knuutila, Sakari
Publicado: (2013)

FGFR-1 amplification in metastatic lymph-nodal and haematogenous lobular breast carcinoma
por: Brunello, Eleonora, et al.
Publicado: (2012)

Molecular Pathology of Pancreatic Cancer: From Bench-to-Bedside Translation
por: Corbo, Vincenzo, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qds0nfsap1l5ggrch20kb0oous