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A novel osteoporosis model with ascorbic acid deficiency in Akr1A1 gene knockout mice

The AKR1A1 protein is a member of the aldo-keto reductase superfamily that is responsible for the conversion of D-glucuronate to L-gulonate in the ascorbic acid (vitamin C) synthesis pathway. In a pCAG-eGFP transgenic mouse line that was produced by pronuclear microinjection, the integration of the...

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Detalles Bibliográficos
Autores principales: Lai, Cheng-Wei, Chen, Hsiao-Ling, Tu, Min-Yu, Lin, Wei-Yu, Röhrig, Theresa, Yang, Shang-Hsun, Lan, Ying-Wei, Chong, Kowit-Yu, Chen, Chuan-Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352327/
https://www.ncbi.nlm.nih.gov/pubmed/28060768
http://dx.doi.org/10.18632/oncotarget.14458