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A novel osteoporosis model with ascorbic acid deficiency in Akr1A1 gene knockout mice
The AKR1A1 protein is a member of the aldo-keto reductase superfamily that is responsible for the conversion of D-glucuronate to L-gulonate in the ascorbic acid (vitamin C) synthesis pathway. In a pCAG-eGFP transgenic mouse line that was produced by pronuclear microinjection, the integration of the...
Autores principales: | Lai, Cheng-Wei, Chen, Hsiao-Ling, Tu, Min-Yu, Lin, Wei-Yu, Röhrig, Theresa, Yang, Shang-Hsun, Lan, Ying-Wei, Chong, Kowit-Yu, Chen, Chuan-Mu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352327/ https://www.ncbi.nlm.nih.gov/pubmed/28060768 http://dx.doi.org/10.18632/oncotarget.14458 |
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