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Aryl hydrocarbon receptor regulates histone deacetylase 8 expression to repress tumor suppressive activity in hepatocellular carcinoma

Histone deacetylase 8 (HDAC8), a unique member of class I histone deacetylases, shows remarkable correlation with advanced disease stage and multiple malignant tumors However, little is known about the contribution of HDAC8 to the tumorigenesis of hepatocellular carcinoma (HCC). The present study in...

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Detalles Bibliográficos
Autores principales: Wang, Li-Ting, Chiou, Shyh-Shin, Chai, Chee-Yin, Hsi, Edward, Wang, Shen-Nien, Huang, Shau-Ku, Hsu, Shih-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352337/
https://www.ncbi.nlm.nih.gov/pubmed/27283490
http://dx.doi.org/10.18632/oncotarget.9841