BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers

Here, BTG1 overexpression inhibited proliferation, induced differentiation, autophagy, and apoptosis in colorectal cancer cells (p(2) arrest might be related to Cyclin B1 and Cdc25B hypoexpression in HCT-15 transfectants, while G(1) arrest in HCT-116 transfectants overexpressing p21 and p27. BTG1 ov...

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Detalles Bibliográficos
Autores principales: Zhao, Shuang, Chen, Shu-rui, Yang, Xue-feng, Shen, Dao-fu, Takano, Yasuo, Su, Rong-jian, Zheng, Hua-chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352338/
https://www.ncbi.nlm.nih.gov/pubmed/27447746
http://dx.doi.org/10.18632/oncotarget.10649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352338/
https://www.ncbi.nlm.nih.gov/pubmed/27447746
http://dx.doi.org/10.18632/oncotarget.10649

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