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BTG1 might be employed as a biomarker for carcinogenesis and a target for gene therapy in colorectal cancers
Here, BTG1 overexpression inhibited proliferation, induced differentiation, autophagy, and apoptosis in colorectal cancer cells (p(2) arrest might be related to Cyclin B1 and Cdc25B hypoexpression in HCT-15 transfectants, while G(1) arrest in HCT-116 transfectants overexpressing p21 and p27. BTG1 ov...
Autores principales: | Zhao, Shuang, Chen, Shu-rui, Yang, Xue-feng, Shen, Dao-fu, Takano, Yasuo, Su, Rong-jian, Zheng, Hua-chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352338/ https://www.ncbi.nlm.nih.gov/pubmed/27447746 http://dx.doi.org/10.18632/oncotarget.10649 |
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