The immunomodulatory effects of TNF-α inhibitors on human Th17 cells via RORγt histone acetylation

The presence of interleukin (IL)-17-related cytokines correlates with rheumatoid arthritis (RA) pathogenesis. Epigenetic modifications, including histone acetylation, regulate gene expression in RA pathogenesis. Tumour necrosis factor-alpha (TNF-α) inhibitors such as etanercept and adalimumab, repre...

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Detalles Bibliográficos
Autores principales: Lin, Yi-Ching, Lin, Yu-Chih, Wu, Cheng-Chin, Huang, Ming-Yii, Tsai, Wen-Chan, Hung, Chih-Hsing, Kuo, Po-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352343/
https://www.ncbi.nlm.nih.gov/pubmed/27926504
http://dx.doi.org/10.18632/oncotarget.13791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352343/
https://www.ncbi.nlm.nih.gov/pubmed/27926504
http://dx.doi.org/10.18632/oncotarget.13791

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