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Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound
Hypoxia occurs in a variety of pathological events, including the formation of solid tumors. Hypoxia-inducible factor (HIF)-1α is stabilized under hypoxic conditions and is a key molecule in tumor growth and angiogenesis. Seeking to develop novel cancer therapeutics, we investigated small molecules...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352362/ https://www.ncbi.nlm.nih.gov/pubmed/27999195 http://dx.doi.org/10.18632/oncotarget.13955 |