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CHIR99021 combined with retinoic acid promotes the differentiation of primordial germ cells from human embryonic stem cells
Primordial germ cells (PGCs) derived from human embryonic stem cells (hESCs) represent as a desirable experimental model as well as a potential strategy for treating male infertility. Here, we developed a simple and feasible method for differentiation of PGCs from hESCs by using CHIR99021 (an inhibi...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352363/ https://www.ncbi.nlm.nih.gov/pubmed/27999196 http://dx.doi.org/10.18632/oncotarget.13958 |