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Rottlerin exhibits antitumor activity via down-regulation of TAZ in non-small cell lung cancer

Rottlerin, a polyphenolic compound derived from Mallotus philipinensis, has been reported to exhibit anti-tumor activities in a variety of human malignancies including NSCLC (non-small cell lung cancer). TAZ (transcriptional co-activator with PDZ-binding motif), one of the key activators in Hippo pa...

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Detalles Bibliográficos
Autores principales: Zhao, Zhe, Zheng, Nana, Wang, Lixia, Hou, Yingying, Zhou, Xiuxia, Wang, Zhiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352364/
https://www.ncbi.nlm.nih.gov/pubmed/27999199
http://dx.doi.org/10.18632/oncotarget.13974