Metalloproteinase meprin α regulates migration and invasion of human hepatocarcinoma cells and is a mediator of the oncoprotein Reptin

Hepatocellular carcinoma is associated with a high rate of intra-hepatic invasion that carries a poor prognosis. Meprin alpha (Mep1A) is a secreted metalloproteinase with many substrates relevant to cancer invasion. We found that Mep1A was a target of Reptin, a protein that is oncogenic in HCC. We s...

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Detalles Bibliográficos
Autores principales: Breig, Osman, Yates, Maïlyn, Neaud, Véronique, Couchy, Gabrielle, Grigoletto, Aude, Lucchesi, Carlo, Prox, Johannes, Zucman-Rossi, Jessica, Becker-Pauly, Christoph, Rosenbaum, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352365/
https://www.ncbi.nlm.nih.gov/pubmed/27999200
http://dx.doi.org/10.18632/oncotarget.13975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352365/
https://www.ncbi.nlm.nih.gov/pubmed/27999200
http://dx.doi.org/10.18632/oncotarget.13975

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