Early pathogenic event of Alzheimer’s disease documented in iPSCs from patients with PSEN1 mutations

Alzheimer's disease (AD) is the most common age-related dementia characterized by progressive neuronal loss. However, the molecular mechanisms for the neuronal loss is still debated. Here, we used induced pluripotent stem cells (iPSCs) derived from somatic cells of familial AD patients carrying...

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Detalles Bibliográficos
Autores principales: Yang, Juan, Zhao, Hanzhi, Ma, Yu, Shi, Guilai, Song, Jian, Tang, Yu, Li, Song, Li, Ting, Liu, Nan, Tang, Fan, Gu, Junjie, Zhang, Lingling, Zhang, Zhuohua, Zhang, Xiaohui, Jin, Ying, Le, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352369/
https://www.ncbi.nlm.nih.gov/pubmed/27926491
http://dx.doi.org/10.18632/oncotarget.13776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352369/
https://www.ncbi.nlm.nih.gov/pubmed/27926491
http://dx.doi.org/10.18632/oncotarget.13776

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