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Ikaros regulation of the BCL6/BACH2 axis and its clinical relevance in acute lymphoblastic leukemia

B-Cell CLL/Lymphoma 6 (BCL6) is a proto-oncogene that is highly expressed in acute lymphoblastic leukemia (ALL). BTB and CNC Homology 1 Basic Leucine Zipper Transcription Factor 2 (BACH2) is a suppressor of transcription. The BACH2–BCL6 balance controls selection at the pre-B cell receptor checkpoin...

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Detalles Bibliográficos
Autores principales: Ge, Zheng, Zhou, Xilian, Gu, Yan, Han, Qi, Li, Jianyong, Chen, Baoan, Ge, Qinyu, Dovat, Elanora, Payne, Jonathon L., Sun, Tianyu, Song, Chunhua, Dovat, Sinisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352379/
https://www.ncbi.nlm.nih.gov/pubmed/28030830
http://dx.doi.org/10.18632/oncotarget.14038