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The secretion and biological function of tumor suppressor maspin as an exosome cargo protein

Maspin is an epithelial-specific tumor suppressor shown to exert its biological effects as an intracellular, cell membrane-associated, and secreted free molecule. A recent study suggests that upon DNA-damaging g-irradiation, tumor cells can secrete maspin as an exosome-associated protein. To date, t...

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Detalles Bibliográficos
Autores principales: Dean, Ivory, Dzinic, Sijana H, Bernardo, M. Margarida, Zou, Yi, Kimler, Vickie, Li, Xiaohua, Kaplun, Alexander, Granneman, James, Mao, Guangzhao, Sheng, Shijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352381/
https://www.ncbi.nlm.nih.gov/pubmed/28009978
http://dx.doi.org/10.18632/oncotarget.13302