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Inhibition of gamma-secretase in Notch1 signaling pathway as a novel treatment for ovarian cancer
Epithelial ovarian cancer (EOC) is the leading cause of death for gynecological cancer. Most patients are not diagnosed until the cancer is at an advanced stage with poor prognosis. Notch1 signaling pathway plays an oncogenic role in EOC. There have been few studies on enzymatic activity of γ-secret...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352395/ https://www.ncbi.nlm.nih.gov/pubmed/28030808 http://dx.doi.org/10.18632/oncotarget.14152 |