Stattic and metformin inhibit brain tumor initiating cells by reducing STAT3-phosphorylation

Glioblastoma (GBM) is the most common and malignant type of primary brain tumor and associated with a devastating prognosis. Signal transducer and activator of transcription number 3 (STAT3) is an important pathogenic factor in GBM and can be specifically inhibited with Stattic. Metformin inhibits G...

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Detalles Bibliográficos
Autores principales: Leidgens, Verena, Proske, Judith, Rauer, Lisa, Moeckel, Sylvia, Renner, Kathrin, Bogdahn, Ulrich, Riemenschneider, Markus J., Proescholdt, Martin, Vollmann-Zwerenz, Arabel, Hau, Peter, Seliger, Corinna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352398/
https://www.ncbi.nlm.nih.gov/pubmed/28030813
http://dx.doi.org/10.18632/oncotarget.14159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352398/
https://www.ncbi.nlm.nih.gov/pubmed/28030813
http://dx.doi.org/10.18632/oncotarget.14159

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