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Paeoniflorin ameliorates interferon-alpha-induced neuroinflammation and depressive-like behaviors in mice
Long-term treatment with high-dose Interferon-alpha (IFN-α) has resulted in depression in 30–50% of the patients. Paeoniflorin may ameliorate the IFN-α-induced depression; however, the underlying mechanism is less studied. Here, we investigated the prophylactic antidepressant and anti-neuroinflammat...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352399/ https://www.ncbi.nlm.nih.gov/pubmed/28030814 http://dx.doi.org/10.18632/oncotarget.14160 |