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MRTF-A can activate Nrf2 to increase the resistance to doxorubicin

Chemotherapeutic drugs resistance was considered to be the major obstacle for cancer therapy. MRTF-A, co-activators of serum response factor (SRF), promoted tumor cell invasion and metastasis in cancer. So far there has been no relevant reports about MRTF-A’ role in tumor chemotherapy. Here, we repo...

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Detalles Bibliográficos
Autores principales: Xu, Yao, Luo, Ying, Wang, Zhen-yu, Li, Xi, Zheng, Peng, Zhang, Tong-cun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352412/
https://www.ncbi.nlm.nih.gov/pubmed/28035058
http://dx.doi.org/10.18632/oncotarget.14246