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The angiotensin II type 1 receptor antagonist telmisartan inhibits cell proliferation and tumor growth of esophageal adenocarcinoma via the AMPKa/mTOR pathway in vitro and in vivo

Telmisartan, a widely used antihypertensive drug, is an angiotensin II type 1 (AT1) receptor blocker (ARB). This drug inhibits cancer cell proliferation, but the underlying mechanisms in various cancers, including esophageal cancer, remain unknown. The aim of the present study was to evaluate the ef...

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Detalles Bibliográficos
Autores principales: Fujihara, Shintaro, Morishita, Asahiro, Ogawa, Kana, Tadokoro, Tomoko, Chiyo, Taiga, Kato, Kiyohito, Kobara, Hideki, Mori, Hirohito, Iwama, Hisakazu, Masaki, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352420/
https://www.ncbi.nlm.nih.gov/pubmed/28052030
http://dx.doi.org/10.18632/oncotarget.14345